Isabella I (Spanish: Isabel I; 22 April 1451 – 26 November 1504), also called Isabella the Catholic (Spanish: Isabel la Católica), was Queen of Castile and León from 1474 until her death in 1504. She was also Queen of Aragon from 1479 until her death as the wife of King Ferdinand II. Reigning together over a dynastically unified Spain, Isabella and Ferdinand are known as the Catholic Monarchs. Her reign marked the end of Reconquista and also the start of Spanish Empire and dominance of Spain over European Politics for the next century.
https://en.wikipedia.org/wiki/Isabella_I_of_Castile