House Harkonnen (/ˈhɑrkɵnən/[1] or /hɑrˈkoʊnən/) is a powerful noble family in Frank Herbert's fictional Dune Science Fiction universe.
The Harkonnens are featured prominently in the original 1965 novel, and are also a major presence in both the Prelude to Dune (1999-2001) and Legends of Dune (2002-2004) prequel trilogies by Brian Herbert and Kevin J. Anderson. The Harkonnen bloodline itself extends throughout all of the original Dune novels.