Dust Of Osiris's main weapon in Melty Blood Actress Again. A Spiriton Computer, which will keep all records of humanity eternally.
With the crystallization of the planet and all of mankind transformed into Philosopher's stones, the circuit of Hermes, after drinking them, will continually think of the assumption that humans still survive, even after mankind has died out and the planet has cooled.
In Fate/EXTRA, Hermes serves as the core of Rani VIIi.