Meme stemming from a typo in Tsukihime, wherein Hisui (Tsukihime)'s line "anata wa hannin desu" ("you are the criminal/culprit") was misprinted in the game as "anata wo hannin desu" ("you, be the criminal/culprit!").
This incident was seized upon by fans and Type-Moon alike, and gave rise to the Hisui brainwashing meme, as well as the Brainwasher Detective character.